Yes, for most systems with SSDs. If the system disk is an SSD, and the SSD performs adequately on random reads and doesn't have glaring performance issues with random writes or flushes, then Superfetch, boot prefetching, application launch prefetching, ReadyBoost and ReadDrive will all be disabled.
* Windows SuperFetch SuperFetch enables programs and files to load quickly. SuperFetch monitors which applications you use the most and preloads these into your system memory so they will be ready when you need them ( This is used in Windows Vista and Windows 7 Operating systems)
*The prefetch folder is used for speeding up your system. The way it does this is by doing the following:
• Windows XP is configured to prefetch application and program components so that when you load them to memory; it appears to be very quick.
• When XP does this the first time, it winds up copying portions of the program to the prefetch area of your local disk.
• When XP boots up, XP will prefetch portions of the files you use the most.
• XP loads all associated files, libraries, and pointers necessary to run the program in advance, the preloaded subset makes your system appear quicker.